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OXA β-lactamases from <i>Acinetobacter</i> spp. are membrane-bound and secreted into outer membrane vesicles

2024-11-07

Abstract excerpt

<h4>ABSTRACT</h4> β-lactamases from Gram-negative bacteria are generally regarded as soluble, periplasmic enzymes. NDMs have been exceptionally characterized as lipoproteins anchored to the outer membrane. A bioinformatics study on all sequenced β-lactamases was performed that revealed a predominance of putative lipidated enzymes in the class D OXAs. Namely, 60% of the OXA class D enzymes contain a lipobox sequen...

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Literature Corpus work
802d045f-b6fa-5a12-8c4d-0c24cd15c085
DOI
10.1101/2024.11.04.622015
Open publication

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OXA β-lactamases from <i>Acinetobacter</i> spp. are membrane-bound and secreted into outer membrane vesiclesDOI 10.1101/2024.11.04.622015
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