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Genetic synergy in <i>Acinetobacter baumannii</i> undecaprenyl biosynthesis and maintenance of lipid asymmetry impacts outer membrane and antimicrobial resistance

2023-09-22

Abstract excerpt

Acinetobacter baumannii is a Gram-negative healthcare-associated pathogen that poses a major health concern due to increasing multidrug resistance. The Gram-negative cell envelope is a key barrier to antimicrobial entry and includes an inner and outer membrane. The outer membrane has an asymmetric composition that is important for structural integrity and barrier to the environment. Therefore, Gram-negative bacter...

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Literature Corpus work
47e1b776-4fc4-5913-bb8e-0f49466fe1aa
DOI
10.1101/2023.09.22.556980
Open publication

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