Article

Dihydroartemisinin exerts multiple effects in ameliorating CNS inflammation by enhancing AXL signaling in microglia from mouse model of multiple sclerosis

2020-02-13

Abstract excerpt

<h4>Background: </h4> Dihydroartemisinin (DHA), a bioactive sesquiterpenoids originated from Artemisia annua L. , extensively applied in traditional medicine for the treatment of multiple autoimmune diseases. AXL, shown to dampen the immune response, reduce pro-inflammatory cytokine secretion, clear apoptotic cells and debris in Multiple sclerosis (MS), suggesting that it plays a role in disease pathogenesis. Thus...

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Literature Corpus work: eafd08b4-5076-5f40-a348-3acec1991521
DOI: 10.21203/rs.2.23348/v1

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