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Article

Can we switch microglia's phenotype to foster neuroprotection? Focus on multiple sclerosis.

Immunology - 1 Mar 2014

Giunti Debora, Parodi Benedetta, Cordano Christian, Uccelli Antonio, Kerlero de Rosbo Nicole

Abstract excerpt

Microglia cells, the resident innate immune cells in the brain, are highly active, extending and retracting highly motile processes through which they continuously survey their microenvironment for 'danger signals' and interact dynamically with surrounding cells. Upon sensing changes in their central nervous system microenvironment, microglia become activated, undergoing morphological and functional changes....

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Identifiers

PMID: 24116890
DOI: 10.1111/imm.12177
PMCID: PMC3930371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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