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Article

Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis.

Frontiers in immunology - 1 Jan 2018

Li Xing, Zhao Li, Han Juan-Juan, Zhang Fei, Liu Shuai, Zhu Lin, Wang Zhe-Zhi, Zhang Guang-Xian, Zhang Yuan

Abstract excerpt

Medicinal plants as a rich pool for developing novel small molecule therapeutic medicine have been used for thousands of years. Carnosol as a bioactive diterpene compound originated from Rosmarinus officinalis (Rosemary) and Salvia officinalis, herbs extensively applied in traditional medicine for the treatment of multiple autoimmune diseases (1). In this study, we investigated the therapeutic effects and...

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Encephalomyelitis, Autoimmune, Experimental
Immunomodulation
Microglia
Multiple Sclerosis
NF-kappa B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

STAT3 Transcription Factor

T-Lymphocyte Subsets

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Identifiers

PMID: 30150982
DOI: 10.3389/fimmu.2018.01807
PMCID: PMC6100297

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