Article

miRNA-485 Regulates Th17 Generation and Pathogenesis in Experimental Autoimmune Encephalomyelitis through Targeting STAT3

2022-10-19

Abstract excerpt

<title>Abstract</title><p>Experimental autoimmune encephalomyelitis (EAE) refers to the T-helper (Th) cell-induced autoimmune disease causing demyelination, axonal loss, as well as neurodegeneration of central nervous system (CNS). EAE pathogenesis is highly dependent on T-helper 17 cells (Th17) that generate interleukin-17 (IL-17), and their activity and differentiation are tightly regulated by some cytokines and...

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Literature Corpus work: eaef6d4a-a472-5a49-9b35-1b79346e79dc
DOI: 10.21203/rs.3.rs-2151273/v1

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