Article

ROMO1 and Mitochondrial Complex II/SDH are Required for Spare Respiratory Capacity and Glucose Homeostasis in Mice

2021-04-28

Abstract excerpt

<h4>Aims/Hypothesis</h4> Reactive oxygen species modulator 1 (ROMO1) is a highly conserved inner mitochondrial membrane protein that senses reactive oxygen species and regulates mitochondrial dynamics. ROMO1 is required for mitochondrial fusion in vitro , and silencing ROMO1 increases sensitivity to cell death stimuli. The physiological role of ROMO1 remains unclear. <h4>Methods</h4> To determine the role of R...

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Literature Corpus work: eae0b4a6-76d4-582a-b4ce-024e7b402971
DOI: 10.1101/2021.04.28.441811

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