Article

Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function

2020-09-16

Abstract excerpt

<h4>Background</h4> The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from non-primate hosts to humans. Tests for positive selection can identify apparently nonrandom patterns of mutation accumulation within genomes, highlighting regions where molecular funct...

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Literature Corpus work: eaa29e9e-025f-5608-baf2-1925258900e7
DOI: 10.1101/2020.09.16.300038

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