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Article

SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes

2020-06-03

Abstract excerpt

<h4>Summary</h4> Despite its overwhelming clinical importance, the SARS-CoV-2 gene set remains unresolved, hindering dissection of COVID-19 biology. Here, we use comparative genomics to provide a high-confidence protein-coding gene set, characterize protein-level and nucleotide-level evolutionary constraint, and prioritize functional mutations from the ongoing COVID-19 pandemic. We select 44 complete Sarbecovirus...

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Literature Corpus work
ef726dfa-0b40-5e70-ad16-63bbf46013e5
DOI
10.1101/2020.06.02.130955
Open publication

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SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomesDOI 10.1101/2020.06.02.130955
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