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Article

SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomes

2020-10-01

Abstract excerpt

<title>Abstract</title> <p>Despite its overwhelming clinical importance, the SARS-CoV-2 gene set remains unresolved, hindering dissection of COVID-19 biology. Here, we use comparative genomics to provide a high-confidence protein-coding gene set, characterize protein-level and nucleotide-level evolutionary constraint, and prioritize functional mutations from the ongoing COVID-19 pandemic. We select 44 complete Sa...

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Identifiers and source

Literature Corpus work
978a1579-4a28-544d-ab33-7305b2b5df5f
DOI
10.21203/rs.3.rs-80345/v1
Open publication

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SARS-CoV-2 gene content and COVID-19 mutation impact by comparing 44 Sarbecovirus genomesDOI 10.21203/rs.3.rs-80345/v1
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