Article

Molecular Evolution of SARS-CoV-2 Structural Genes: Evidence of Positive Selection in the Spike Glycoprotein

2020-08-31

Abstract excerpt

<h4>Background: </h4> SARS-CoV-2 has caused a global pandemic since early 2020 and remains a serious public health issue worldwide. Four structural genes, envelope (E), membrane (M), nucleocapsid (N) and spike (S), play a key role in controlling entry into human cells and virion assembly of SARS-CoV-2. The evolution of these genes may determine infectivity of SARS-CoV-2, but thus far, little is known about them. <...

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Literature Corpus work: 613c0353-a789-58f8-b697-e84ec5de4047
DOI: 10.21203/rs.3.rs-42498/v2

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