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Comparative Genomic Analyses Reveal a Specific Mutation Pattern Between Human Coronavirus SARS-CoV-2 and Bat-CoV RaTG13

29 Nov 2020

Abstract excerpt

BACKGROUND: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, rapidly grew into a global pandemic. How SARS-CoV-2 evolved remains unclear. METHODS: We performed a comprehensive analysis using the available genomes of SARS-CoV-2 and its closely related coronaviruses. RESULTS: The ratio of nucleotide substitutions to amino acid substitutions of the spike gene (9.07)...

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PMID: 33424784
DOI: 10.3389/fmicb.2020.584717

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