Article

<i>C. elegans</i> RIG-I-like receptor DRH-1 signals via CARDs to activate anti-viral immunity in intestinal cells

2024-02-08

Abstract excerpt

Upon sensing viral RNA, mammalian RIG-I-like receptors activate downstream signals using caspase activation and recruitment domains (CARDs), which ultimately promote transcriptional immune responses that have been well-studied. In contrast, the downstream signaling mechanisms for invertebrate RIG-I-like receptors are much less clear. For example, the Caenorhabditis elegans RIG-I-like receptor DRH-1 lacks annotate...

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Literature Corpus work: ea8d80ea-dde4-5b99-8817-c7de9366f37e
DOI: 10.1101/2024.02.05.578694

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