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The Innate Antiviral Response in Animals: An Evolutionary Perspective from Flagellates to Humans

16 Aug 2019

Abstract excerpt

Animal cells have evolved dedicated molecular systems for sensing and delivering a coordinated response to viral threats. Our understanding of these pathways is almost entirely defined by studies in humans or model organisms like mice, fruit flies and worms. However, new genomic and functional data from organisms such as sponges, anemones and mollusks are helping redefine our understanding of these immune systems...

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PMID: 31426357
DOI: 10.3390/v11080758

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