Article

An engineered platform to study the influence of extracellular matrix nanotopography on cell ultrastructure

2025-03-03

Abstract excerpt

Nanoscale fabrication techniques have played an essential role in revealing the impact of extracellular matrix (ECM) nanotopography on cellular behavior. However, the mechanisms by which nanotopographical cues from the ECM influence cellular function remain unclear. To approach these questions, we have engineered a novel class of nanopatterned ECM constructs suitable for cryogenic electron tomography (cryo-ET), th...

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Literature Corpus work: ea7ed67c-31aa-5b9b-bdb7-00d34b46ecd6
DOI: 10.1101/2025.02.27.640302

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