Article

Recombinant Bacillus subtilis for Enhanced Production of High Molecular Weight Hyaluronic Acid

2023-11-26

Abstract excerpt

<title>Abstract</title> <p>This study aimed to synthesize hyaluronic acid (HA) using a non-pathogenic, recombinant bacterial host, specifically <italic>Bacillus subtilis</italic> 1A752. The hyaluronic acid synthase (HAS) gene<italic>, hasA</italic>, originally isolated from <italic>Streptococcus equi subsp. zooepidemicus</italic>, was introduced into <italic>B. subtilis </italic>1A752. This host strain already ha...

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Literature Corpus work: ea7cd50f-3e3c-5280-94ae-0cc043a8a564
DOI: 10.21203/rs.3.rs-3349457/v1

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