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[Construction and characterization of hemolysin S gene mutant strain producing hyaluronic acid].

Wei sheng wu xue bao = Acta microbiologica Sinica - 4 Nov 2016

Liu Yuchuan, Li Yuxing, Lai Yongqin, Li Xueru, Huang Xinhe, Guo Tailin, Yao Ning

Abstract excerpt

Objective: Streptococcus equi subsp. zooepidemicus (GCS) is mainly used to produce hyaluronic acid (HA) in the industry. GCS secretes the hemolysis toxin (streptolysin S, SLS) that causes hemolysis in the host cells. Therefore, the safety of HA produced by GCS is concerned. We constructed an engineering strain, to produce commercial HA without SLS by knocking out saga. Method: The sagA of GCS was knocked out by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29741839

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SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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