Article

Mechanisms of Immunomodulation and Cytoprotection Conferred to Pancreatic Islet by Human Amniotic Epithelial Cells

2021-07-13

Abstract excerpt

<title>Abstract</title> <p>Inhibiting pro-inflammatory cytokine activity can reverse inflammation mediated dysfunction of islet grafts. Human amniotic epithelial cells (hAECs) possess regenerative, immunomodulatory and anti-inflammatory properties. We hypothesized that hAECs could protect islets from cellular damage induced by pro-inflammatory cytokines. To verify our hypothesis hAECs monocultures, rat islets (RI...

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Literature Corpus work: 204b1b66-9b8a-53c3-bc3a-0f84f9339237
DOI: 10.21203/rs.3.rs-236761/v2

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