Article

Rejuvenation of mesenchymal stem cells by human peripheral blood lymphocytes: A dual-mechanism for targeting senescent cell clearance and promoting cell proliferation in a coculture system

2025-04-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: In the in-vitro expansion of mesenchymal stem cells (MSCs), replicative or stress-induced senescence poses a significant challenge, leading to the loss of their cellular properties and therapeutic functions. Currently, there is a lack of efficient strategies to address this issue. <bold>Methods</bold>: Here we presented a novel approach to combat cellular senesc...

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Literature Corpus work: 7a2a0f93-2541-5dd1-9254-c3848fe35bff
DOI: 10.21203/rs.3.rs-5848058/v1

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