Article

Human Adipose-Derived Stem Cells Genetically Programmed to Induce Necroptosis for Cancer Immunotherapy

2024-03-13

Abstract excerpt

<title>Abstract</title> <p>Herein, we present human adipose-derived stem cells (ADSCs) inserted with the receptor-interacting protein kinase-3 (RIP3) gene (RP@ADSCs), which induces cell necroptosis for tumor immunotherapy. Necroptosis has characteristics of both apoptosis, such as programmed cell death, and necrosis, such as swelling and plasma membrane rupture, during which damage-related molecular patterns are...

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Literature Corpus work: d4b74e29-822b-5179-8ec7-94253ec4eace
DOI: 10.21203/rs.3.rs-4021102/v1

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