Article

Constitutively active receptor ADGRA3 signaling induces adipose thermogenesis

2024-06-08

Abstract excerpt

<h4>ABSTRACT</h4> The induction of adipose thermogenesis plays a critical role in maintaining body temperature and improving metabolic homeostasis to combat obesity. β3-adrenoceptor (β3-AR) is widely recognized as a canonical β-adrenergic G protein-coupled receptor (GPCR) that plays a crucial role in mediating adipose thermogenesis in mice. Nonetheless, the limited expression of β3-AR in human adipocytes restrict...

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Literature Corpus work: ea5b1d88-f1f4-5864-80f7-c0b3b67e5c77
DOI: 10.1101/2024.06.08.598066

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