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Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells

7 Mar 2017

Abstract excerpt

Activation of thermogenic beige adipocytes has recently emerged as a promising therapeutic target in obesity and diabetes. Relevant human models for beige adipocyte differentiation are essential to implement such therapeutic strategies. We report a straightforward and efficient protocol to generate functional human beige adipocytes from human induced pluripotent stem cells (hiPSCs). Without overexpression of...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 28270520
DOI: 10.2337/db16-1107

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