Back to search

Article

Improving the coverage of credible sets in Bayesian genetic fine-mapping

2019-09-25

Abstract excerpt

Genome Wide Association Studies (GWAS) have successfully identified thousands of loci associated with human diseases. Bayesian genetic fine-mapping studies aim to identify the specific causal variants within GWAS loci responsible for each association, reporting credible sets of plausible causal variants, which are interpreted as containing the causal variant with some “coverage probability”. Here, we use simulatio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e9efd08c-0120-51cf-9e82-836604e15c77
DOI
10.1101/781062
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Improving the coverage of credible sets in Bayesian genetic fine-mappingDOI 10.1101/781062
Select a neighboring publication to make it the new centre.