Article
Improving the coverage of credible sets in Bayesian genetic fine-mapping.
PLoS computational biology - 1 Apr 2020
Hutchinson Anna, Watson Hope, Wallace Chris
Abstract excerpt
Genome Wide Association Studies (GWAS) have successfully identified thousands of loci associated with human diseases. Bayesian genetic fine-mapping studies aim to identify the specific causal variants within GWAS loci responsible for each association, reporting credible sets of plausible causal variants, which are interpreted as containing the causal variant with some "coverage probability". Here, we use...
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