Article

Insulin-induced Gene 2 Protects against Hepatic Ischemia-reperfusion Injury via Metabolic Remodeling

2023-06-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>Hepatic ischemia-reperfusion (IR) injury is the primary reason for complications following hepatectomy and liver transplantation (LT). Insulin-induced gene 2 (Insig2) is one of several proteins that anchor the reticulum in the cytoplasm and is essential for metabolism and inflammatory responses. However, its function in IR injury remains ambiguous. <bold>Methods:...

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Literature Corpus work: e9d9d105-798a-5c37-b480-be462267ad19
DOI: 10.21203/rs.3.rs-2959054/v1

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