Article

Examination of signatures of recent positive selection on genes involved in human sialic acid biology

2017-05-11

Abstract excerpt

<h4> Abstract </h4> Sialic acids are nine carbon sugars ubiquitously found on the surfaces of vertebrate cells and are involved in various immune response-related processes. In humans, at least 58 genes spanning diverse functions, from biosynthesis and activation to recycling and degradation, are involved in sialic acid biology. Because of their role in immunity, sialic acid biology genes have been hypothesized...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e9c7285d-46e7-565e-9678-3e9401fbcb98
DOI: 10.1101/137034

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Examination of signatures of recent positive selection on genes involved in human sialic acid biologyDOI 10.1101/137034Read

Examination of Signatures of Recent Positive Selection on Genes Involved in Human Sialic Acid Biology.Semantic proximity Read

Uniquely human evolution of sialic acid genetics and biologySemantic proximity Read

Multiple Genomic Events Altering Hominin SIGLEC Biology and Innate Immunity Predated the Common Ancestor of Humans and Archaic Hominins.Semantic proximity Read

Multiple changes in sialic acid biology during human evolution.Semantic proximity Read

The impact of natural selection on the evolution and function of placentally expressed galectinsSemantic proximity Read

Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes.Semantic proximity Read

Immune-driven positive and balancing selection in human populationsSemantic proximity Read

A second uniquely human mutation affecting sialic acid biology.Semantic proximity Read

Human gut metagenomes encode diverse GH156 sialidasesSemantic proximity Read

Recent evolution of the salivary mucin MUC7.Semantic proximity Read

Genetic differences between humans and great apes.Semantic proximity Read

Biomedical Differences Between Human and Nonhuman Hominids: Potential Roles for Uniquely Human Aspects of Sialic Acid BiologySemantic proximity Read