Article
Examination of Signatures of Recent Positive Selection on Genes Involved in Human Sialic Acid Biology.
G3 (Bethesda, Md.) - 28 Mar 2018
Moon Jiyun M, Aronoff David M, Capra John A, Abbot Patrick, Rokas Antonis
Abstract excerpt
Sialic acids are nine carbon sugars ubiquitously found on the surfaces of vertebrate cells and are involved in various immune response-related processes. In humans, at least 58 genes spanning diverse functions, from biosynthesis and activation to recycling and degradation, are involved in sialic acid biology. Because of their role in immunity, sialic acid biology genes have been hypothesized to exhibit elevated...
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