Article

The impact of natural selection on the evolution and function of placentally expressed galectins

2018-12-23

Abstract excerpt

Immunity genes have repeatedly experienced natural selection during mammalian evolution. Galectins are carbohydrate-binding proteins that regulate diverse immune responses, including maternal-fetal immune tolerance in placental pregnancy. Seven human galectins, four conserved across vertebrates and three specific to primates, are involved in placental development. To comprehensively study the molecular evolution o...

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Literature Corpus work: 8a94f0b5-4279-535e-a2dd-7d1e04919bf6
DOI: 10.1101/505339

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