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Microglia Heterogeneity in Alzheimer’s Disease: Insights From Single-Cell Technologies

23 Dec 2021

Abstract excerpt

Microglia are resident immune cells in the central nervous system and play critical roles in brain immunity, development, and homeostasis. The pathology of Alzheimer's disease (AD) triggers activation of microglia. Microglia express many AD risk genes, suggesting that their response to AD pathology can affect disease progression. Microglia have long been considered a homogenous cell population. The diversity of...

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PMID: 35002670
DOI: 10.3389/fnsyn.2021.773590

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