Article

RNAi screening of the tyrosine kinome in primary patient samples of acute myeloid leukemia

2018-01-30

Abstract excerpt

Targeted therapy has proven to be successful in improving outcomes across multiple cancer types. However, many challenges still remain for implementation of this strategy in most patient cohorts, especially with the challenges of identifying the specific mutations or abnormalities in a heterogeneous tumor that are functionally significant. Previously, we developed a functional screening assay, RNAi-assisted protei...

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Literature Corpus work: e9aef35a-2297-5442-a1dc-d65a9441ab03
DOI: 10.1101/256040

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