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Article

The significance of MAPK signaling pathway in the diagnosis and subtype classification of intervertebral disc degeneration

2023-10-12

Abstract excerpt

Intervertebral disc degeneration (IDD) is a human aging disease related mainly to inflammation, cellular senescence, RNA/DNA methylation, and ECM. The mitogen-activated protein kinase (MAPK) signaling pathway is engaged in multiple biological functions by phosphorylating specific serine and threonine residues on target proteins through phosphorylation cascade effects, but the role and specific mechanisms of the MA...

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Literature Corpus work
e9a15c98-57a9-59dd-b96e-d3ce578d2db2
DOI
10.21203/rs.3.rs-3422544/v1
Open publication

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