Article
Identification of the potential molecular targets for human intervertebral disc degeneration based on bioinformatic methods.
International journal of molecular medicine - 1 Dec 2015
He Jiaxuan, Xue Rongliang, Li Siyuan, Lv Jianrui, Zhang Yong, Fan Liying, Teng Yunpeng, Wei Haidong
Abstract excerpt
The present study aimed to explore potential molecular targets and gain further insights into the mechanism of intervertebral disc degeneration (IDD) progression. Microarray datasets of GSE19943, GSE15227 and GSE34095 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) in 3 IDD specimens compared with 3 controls in GSE34095, DEGs in 7 grade III and 3 grade IV samples...
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