Article

Proteogenomic mapping of multimorbidity identifies C1R linking coronary artery disease and dementia

2026-07-16

Abstract excerpt

Multimorbidity is highly prevalent in ageing populations, yet its shared molecular basis remains poorly defined, limiting the development of therapies that target multiple conditions. We systematically integrated measurements of 1,954 circulating proteins from 54,219 individuals in discovery and 35,559 in replication, focusing on ten common age-related diseases: coronary artery disease, chronic kidney disease, chr...

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Literature Corpus work: e98e13be-7db3-51c4-b508-b8dcd7516bd6
DOI: 10.64898/2026.07.14.26358022

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