Article

Cytometric analysis of T cell phenotype using cytokine profiling for improved manufacturing of an EBV-specific T cell therapy.

2021-01-07

Abstract excerpt

Adoptive immunotherapy using Epstein-Barr Virus (EBV)-specific T cells is a potentially curative treatment for patients with EBV-related malignancies where other clinical options have proved ineffective. We describe improved GMP-compliant culture and analysis processes for conventional lymphoblastoid cell line (LCL)-driven EBV-specific T cell manufacture, and describe an improved phenotyping approach for analyzing...

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Literature Corpus work: e94ab3e1-bfbb-5bd6-b720-7abfc88e64a7
DOI: 10.22541/au.161002473.32537816/v1

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