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A Multidimensional Workflow Profiling of Allogeneic EBV-Specific T-cell Therapies Reveals Potency-Linked Signatures

2025-05-15

Abstract excerpt

<title>Abstract</title> <p>Allogeneic Epstein-Barr virus (EBV)-specific T cell therapies offer distinct advantages, including scalability, rapid deployment, and manufacturing consistency, and have demonstrated efficacy in multiple clinical trials. Here, we present a multidimensional analytical platform that integrates in vitro and in vivo anti-viral reactivity, T cell receptor (TCR) repertoire analysis, gene expr...

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Literature Corpus work
276020b7-ade4-52a2-b67a-beaa5f49f091
DOI
10.21203/rs.3.rs-6544259/v1
Open publication

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A Multidimensional Workflow Profiling of Allogeneic EBV-Specific T-cell Therapies Reveals Potency-Linked SignaturesDOI 10.21203/rs.3.rs-6544259/v1
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