Article

Rigorous benchmarking of T cell receptor repertoire profiling methods for cancer RNA sequencing

2022-03-31

Abstract excerpt

The ability to identify and track T cell receptor (TCR) sequences from patient samples is becoming central to the field of cancer research and immunotherapy. Tracking genetically engineered T cells expressing TCRs that target specific tumor antigens is important to determine the persistence of these cells and quantify tumor responses. The available high-throughput method to profile T cell receptor repertoires is g...

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Literature Corpus work: 2025d0b8-f1f7-553f-b370-415df5d50db6
DOI: 10.1101/2022.03.31.22273249

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