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Recent Advances in the Biology and Treatment of T Cell Acute Lymphoblastic Leukemia.

Current hematologic malignancy reports - 1 Aug 2018

Hefazi Mehrdad, Litzow Mark R

Abstract excerpt

PURPOSE OF REVIEW: This article provides an overview of the current knowledge regarding the biology and treatment of T cell acute lymphoblastic leukemia (T-ALL) and highlights the most recent findings in this field over the past 5 years. RECENT FINDINGS: Remarkable progress has been made in the genomic landscape of T-ALL over the past few years. The discovery of activating mutations of NOTCH1 and FBXW7 in a...

Topics

F-Box-WD Repeat-Containing Protein 7
Humans
Mutation
Neoplasm Proteins
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Receptor, Notch1

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29948644
DOI: 10.1007/s11899-018-0455-9

Genes

NOTCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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