Article

Generating the sigmoid form in neuroscience: A threshold-crossing model

2023-11-28

Abstract excerpt

The conventional interpretation 1 of a logistic curve in biology is that it indicates the presence of an infection-like mechanism bounded by a saturation limit e.g. saturation occurs when the whole population has been infected. However, a logistic form may be generated by the fluctuating approach of biological systems to, and then exceeding, an effect threshold. The commonly observed trends in frequency and degr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e9111e77-6fb0-55d3-a769-9309339f1831
DOI: 10.1101/2023.11.27.568902

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Generating the sigmoid form in neuroscience: A threshold-crossing modelDOI 10.1101/2023.11.27.568902Read

The 10 bits/s bottleneck as error-correcting redundancy: an information-theoretic theory of cognitive reserveSemantic proximity Read

Stochastic model of Alzheimer’s Disease progression using two-state Markov chainsSemantic proximity Read

Threshold-dominated regulation hides genetic variation in gene expression networks.Semantic proximity Read

Do Amyloid Trajectories Reach a Physiologic Ceiling? Evidence from Iterative Approximation and SimulationSemantic proximity Read

Metabolic free energy and biological codes: a ‘Data Rate Theorem’ aging modelSemantic proximity Read

The Sensitivity Threshold Model (STM): A Conceptual Framework for Integrating 22 Canonical Findings in SchizophreniaSemantic proximity Read

Foundations of computational psychiatry: a mathematical treatment of embodied cognition and its disordersSemantic proximity Read

Principles underlying implementation of <i>nearly</i> -homeostatic biological networksSemantic proximity Read

Calculating the number of people with Alzheimer's disease in any country using saturated mutation models of brain cell loss that also predict widespread natural immunity to the disease.Semantic proximity Read

The countdown paradox: time-varying analysis of biomarker-clock age and symptom onsetSemantic proximity Read

Metabolic–Attentional Dynamics as a Minimal Generative Mechanism for Subjective TimeSemantic proximity Read

The paradoxical dynamics of prion disease latency.Semantic proximity Read