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Multiple resistance factors collectively promote inoculum-dependent dynamic survival during antimicrobial peptide exposure in <i>Enterobacter cloacae</i>

2024-03-03

Abstract excerpt

Antimicrobial peptides (AMPs) are a promising tool with which to fight rising antibiotic resistance. However, pathogenic bacteria are equipped with several AMP defense mechanisms, whose contributions to AMP resistance are often poorly defined. Here, we evaluate the genetic determinants of resistance to an insect AMP, cecropin B, in the opportunistic pathogen Enterobacter cloacae . Single-cell analysis of E. cloa...

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Literature Corpus work
e8e466d8-a711-5ec8-93fe-753033679ad6
DOI
10.1101/2024.03.03.583169
Open publication

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