Article
Gene expression profiling of Cecropin B-resistant Haemophilus parasuis.
Journal of molecular microbiology and biotechnology - 1 Jan 2014
Wang Chunmei, Chen Fangzhou, Hu Han, Li Wentao, Wang Yang, Chen Pin, Liu Yingyu, Ku Xugang, He Qigai, Chen Huanchun, Xue Feiqun
Abstract excerpt
Synthetically designed antimicrobial peptides (AMPs) present the potential of replacing antibiotics in the treatment of bacterial infections. However, microbial resistance to AMPs has been reported and little is known regarding the underlying mechanism of such resistance. The naturally occurring AMP cecropin B (CB) disrupts the anionic cell membranes of Gram-negative bacteria. In this study, CB resistance (CBR)...
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