Article

Untargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant Leishmania parasites

2019-11-13

Abstract excerpt

<h4>Background: </h4> : Protozoan Leishmania parasites are responsible for a range of clinical infections that represent a substantial challenge for global health. Amphotericin B (AmB) is increasingly used to treat Leishmania infection, so understanding the potential for resistance to this drug is an important priority. Previously we described four independently-derived AmB-resistant L. mexicana lines that exhi...

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Literature Corpus work: e8b97bb0-250d-5d65-a0ab-8555eb40b166
DOI: 10.12688/wellcomeopenres.15452.1

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