Back to search

Article

Metabolic Pathways of Leishmania Parasite: Source of Pertinent Drug Targets and Potent Drug Candidates

2022-06-27

Abstract excerpt

Leishmaniasis is a tropical disease caused by a protozoan parasite Leishmania that is transmitted via infected female sandflies. At present, leishmaniasis treatment mainly counts on chemotherapy. The currently available drugs against leishmaniasis are costly, toxic, with multiple side effects, and limitations in the administration route. The rapid emergence of drug resistance has severely reduced the potency of an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6e851806-36f4-527c-a224-1a96e67b9359
DOI
10.20944/preprints202206.0355.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Metabolic Pathways of Leishmania Parasite: Source of Pertinent Drug Targets and Potent Drug CandidatesDOI 10.20944/preprints202206.0355.v1
An overview of biochemically characterized drug targets in metabolic pathways of Leishmania parasiteSemantic proximity
Emerging therapeutic targets for treatment of leishmaniasisSemantic proximity
In silico Metabolic Pathway Analysis Identifying Target Against Leishmaniasis – A Kinetic Modeling ApproachSemantic proximity
Glycobiology of theLeishmaniaparasite and emerging targets for antileishmanial drug discoverySemantic proximity
Malaria Parasite Metabolic Pathways (MPMP) Upgraded with Targeted Chemical CompoundsSemantic proximity
Omics Approaches in Drug Development against Leishmaniasis: Current Scenario and Future ProspectsSemantic proximity
Metabolomics to unveil and understand phenotypic diversity between pathogen populations.Semantic proximity
Essential gene identification and drug target prioritization in <i>Leishmania</i> speciesSemantic proximity
Antimalarial drug targets and drugs targeting dolichol metabolic pathway of Plasmodium falciparum.Semantic proximity
Molecular Mechanisms of Drug Resistance in Leishmania spp.Semantic proximity
Vitamin and cofactor acquisition in apicomplexans: Synthesis versus salvageSemantic proximity
Lipid and fatty acid metabolism in trypanosomatidsSemantic proximity
Select a neighboring publication to make it the new centre.