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Article

Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs.

International journal for parasitology. Drugs and drug resistance - 1 Aug 2018

Rastrojo Alberto, García-Hernández Raquel, Vargas Paola, Camacho Esther, Corvo Laura, Imamura Hideo, Dujardin Jean-Claude, Castanys Santiago, Aguado Begoña, Gamarro Francisco, Requena Jose M

Abstract excerpt

Leishmaniasis is a serious medical issue in many countries around the World, but it remains largely neglected in terms of research investment for developing new control and treatment measures. No vaccines exist for human use, and the chemotherapeutic agents currently used are scanty. Furthermore, for some drugs, resistance and treatment failure are increasing to alarming levels. The aim of this work was to...

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Identifiers

PMID: 29689531
DOI: 10.1016/j.ijpddr.2018.04.002
PMCID: PMC6039315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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