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Y-mer: A k-mer based method for determining human Y chromosome haplogroups from ultra-low sequencing depth data

2024-10-09

Abstract excerpt

<title>Abstract</title> <p>Determining genetic ancestry of an individual is challenging from poorly preserved or mixed samples that permit only ultra-low sequence (ulcWGS) depth < 0.1x to be gained at target loci. Leveraging the recent advances in telomere-to-telomere sequencing of the whole genomes with long reads we show first in a simplified example how short DNA string (k-mer) copy numbers at two different ty...

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Literature Corpus work: e8aed191-a001-5d11-af99-6467736d371f
DOI: 10.21203/rs.3.rs-5042960/v1

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