Article

Y-mer: A k-mer based method for determining human Y chromosome haplogroups from ultra-low sequencing depth data

2025-06-16

Abstract excerpt

<title>Abstract</title> <p>Determining genetic ancestry of an individual is challenging from poorly preserved or mixed samples that permit only ultra-low coverage sequence (ulcWGS) depth < 0.1x to be gained at target loci. Leveraging the recent advances in telomere-to-telomere sequencing of the whole genomes with long reads we develop a new k-mer based method Y-mer and show how information from hundreds of thousa...

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Literature Corpus work: 25c4e8c6-92f9-5e10-8063-a1fd2460c828
DOI: 10.21203/rs.3.rs-5042960/v2

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