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Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insights

2026-02-12

Abstract excerpt

Body mass index (BMI), type 2 diabetes (T2D) and related cardiometabolic features associate with Alzheimer's disease (AD) risk, yet shared mechanisms remain poorly understood. By combining multi-trait, machine learning and single-cell transcriptomics with genotyping data for BMI and T2D, we investigate how these traits converge on shared genetic pathways to AD risk. Variant-level analyses reveal AD risk associates...

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Literature Corpus work
e8ac2a3c-05b9-5ae4-b827-b2aab4fc9c39
DOI
10.64898/2026.02.10.26344393
Open publication

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Genomics link obesity and type 2 diabetes to Alzheimer's disease to unveil novel biological insightsDOI 10.64898/2026.02.10.26344393
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