Article

BBSome regulation of LITE-1 receptor in a cilium-independent manner in <i>C. elegans</i>

2020-04-28

Abstract excerpt

Bardet-Biedl Syndrome (BBS) is a genetic disorder affecting primary cilia. BBSome, a protein complex composed of eight BBS proteins, regulates the structure and function of cilia in diverse organisms, and its malfunction causes BBS in humans. Here, we report a new function of BBSome in C. elegans . In a forward genetic screen for genes regulating the light sensitivity of the ciliated ASH sensory neurons, we isola...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e8a8672f-639d-53e1-9d54-552d43d84f10
DOI: 10.1101/2020.04.27.064998

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

BBSome regulation of LITE-1 receptor in a cilium-independent manner in <i>C. elegans</i>DOI 10.1101/2020.04.27.064998Read

A cilia-independent function of BBSome mediated by DLK-MAPK signaling in C. elegans photosensationSemantic proximity Read

The sensory cilia of Caenorhabditis elegans_RevisedSemantic proximity Read

Loss of Bardet Biedl syndrome proteins causes defects in peripheral sensory innervation and function.Semantic proximity Read

The Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid compositionSemantic proximity Read

Lifting the lid on Pandora's box: the Bardet-Biedl syndrome.Semantic proximity Read

Loss of C. elegans BBS-7 and BBS-8 protein function results in cilia defects and compromised intraflagellar transport.Semantic proximity Read

Hyperactive Neuroendocrine Secretion Causes Size, Feeding, and Metabolic Defects of C. elegans Bardet-Biedl Syndrome MutantsSemantic proximity Read

Identification and characterization of a novel allele of Caenorhabditis elegans bbs-7.Semantic proximity Read

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in <i>Caenorhabditis elegans</i>Semantic proximity Read

Endocytosis genes facilitate protein and membrane transport in C. elegans sensory cilia.Semantic proximity Read

Functional genomics of the cilium, a sensory organelle.Semantic proximity Read

Generation and characterization of <i>Ccdc28b</i> mutant mice links the Bardet-Biedl associated gene with social behavioral phenotypesSemantic proximity Read