Article

Generation and characterization of <i>Ccdc28b</i> mutant mice links the Bardet-Biedl associated gene with social behavioral phenotypes

2021-10-22

Abstract excerpt

<h4>ABSTRACT</h4> CCDC28B (coiled-coil domain-containing protein 28B) was identified as a modifier in the ciliopathy Bardet-Biedl syndrome (BBS). Our previous work in cells and zebrafish showed that CCDC28B plays a role regulating cilia length in a mechanism that is not completely understood. Here we report the generation of a Ccdc28b mutant mouse using CRISPR/Cas9 ( Ccdc28b mut ). After confirming the depletio...

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Literature Corpus work: fdab03c0-b557-5b61-b307-9d4fa35f00e2
DOI: 10.1101/2021.10.21.465251

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