Article

Benchmarking computational tools for locus-specific analysis of transposable elements in single-cell RNA-seq datasets

2026-02-28

Abstract excerpt

<h4>Background</h4> Transposable elements (TEs) are increasingly recognized as regulators of gene expression and cellular identity in development and disease. Single-cell RNA-sequencing (scRNA-seq) enables the analysis of their transcription at cellular resolution, but the repetitive nature of TEs and their frequent overlap with genes create substantial mapping ambiguity. Although several tools quantify TE expres...

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Literature Corpus work: 5fbde295-28b8-507d-b0df-e1e58ba8309a
DOI: 10.64898/2026.02.26.708244

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