Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact on Glioblastoma U87 Cell Gene Expression of a Carborane Cluster-Bearing Amino Acid: Implications for Carborane Toxicity in Mammalian Cells

26 Nov 2018

Abstract excerpt

Carboranes have been extensively investigated as potential drugs for the treatment of malignant human brain tumors by boron neutron capture therapy (BNCT). This noninvasive treatment modality utilizes compounds containing the nonradioactive isotope 10 B which has a high propensity to capture slow neutrons. In response, it emits high energy α-particles that kill the cell. We have successfully synthesized a boron...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Radiopharmaceutical Chemistry and Applications

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30475580
DOI: 10.1021/acschemneuro.8b00512

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact on Glioblastoma U87 Cell Gene Expression of a Carborane Cluster-Bearing Amino Acid: Implications for Carborane Toxicity in Mammalian CellsPMID 30475580Read ↗

Boron Theranostic Nanoplatform Utilizing a GO@Carborane@Au Hybrid Framework for Targeted DeliverySemantic proximity Read ↗

Clinical Viability of Boron Neutron Capture Therapy for Personalized Radiation TreatmentSemantic proximity Read ↗

Therapeutic Nucleus-Access BNCT Drug Combined CD47-Targeting Gene Editing in GlioblastomaSemantic proximity Read ↗

Translational Evaluation of a Dodecaborated Albumin Conjugate With Maleimide as a Boron Delivery System for a Neutron Capture Reaction to an F98 Rat Glioma ModelSemantic proximity Read ↗

Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.Semantic proximity Read ↗

Biocompatibility evaluation of hexagonal boron nitrides on healthy mouse hippocampal cell line and their positive effect on stressed cellsSemantic proximity Read ↗

Neutron capture enhances dose and reduces cancer cell viability in and out of beam during helium and carbon ion therapySemantic proximity Read ↗

Catalytic modulation of the tumor microenvironment using cascade enzymes for synergistic boron neutron capture therapy in the treatment of gliomasSemantic proximity Read ↗

A Boron Delivery Antibody (BDA) with Boronated Specific Residues: New Perspectives in Boron Neutron Capture Therapy from an In Silico Investigation.Semantic proximity Read ↗

Synchrotron-Based Fourier-Transform Infrared Micro-Spectroscopy (SR-FTIRM) Fingerprint of the Small Anionic Molecule Cobaltabis(dicarbollide) Uptake in Glioma Stem Cells.Semantic proximity Read ↗

Glutathione Transferase-M2-2 Secreted from Glioblastoma Cell Protects SH-SY5Y Cells from Aminochrome NeurotoxicitySemantic proximity Read ↗

Bone marrow-derived macrophages loaded with boron carbide nanoparticles as selective boron carriers for crossing the blood-brain barrier toward the glioma microenvironment for boron neutron capture therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.